Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p362 | (1) | WCRB2014

Nuclear distribution of genotoxic damage in rainbow trout (Oncorhynchus mykiss) sperm after cryopreservation

Gonzalez-Rojo Silvia , Fernandez-Diez Cristina , Lombo Marta , Rodriguez Vanesa Robles , Paz Herraez Maria

Introduction: Sperm DNA is prone to suffer damage that could have a negative impact on the progeny development. Moreover genes packaged in different chromatin blocks or located in different nuclear areas, could have differential sensitivity to genotoxic agents. Our group has demonstrated that in rainbow trout, with the nucleus homogeneously compacted with protamines – lacking histones –, the distribution of damage is dependent on the genotoxic agent. The present work...